Labisia Pumila herb dietary supplement

Labisia pumila plant is known as Kacip Fatimah and has been used by many generations of Malay women to induce and facilitate childbirth as well as a post-partum herbal medicine.

Asmara for Women is a product that has a combination of labisia pumila and Kesum, polygonum minus. Asmara for women is promoted for sexuality vitality libido enhancement, hormonal balance, and wellbeing. Other potential useful herbs for sexuality performance improvement include epimedium, eurcyoma, and maca.

Animal studies

Labisia pumila extract regulates body weight and adipokines in ovariectomized rats.
Maturitas. 2009 Jan 20; Fazliana M, Wan Nazaimoon WM, Gu HF, Ostenson CG. Department of Molecular Medicine and Surgery, M1:03, Karolinska Institutet, Karolinska University Hospital, SE-171 76 Stockholm, Sweden.
We investigated the effects of a standardized water extract of Labisia pumila var. alata, and compared to estrogen replacement (ERT), on body weight gain, uterus weight, adipose tissue mRNA and protein levels of adipokines in ovariectomized (OVX) rats. Eight-week-old OVX Sprague-Dawley rats were administered orally with either 10 mg/kg/day Labisia pumila 10), 20 mg/kg/day ( Labisia pumila 20) or 50 mg/kg/day (Labisia pumila 50) of Labisia pumila for 30 days. ERT- and Labisia pumila 50-treated OVX rats showed significantly less weight gain compared to untreated OVX rats. Ovariectomy caused plasma leptin levels to decrease significantly, but when treated with Labisia pumila or ERT, plasma leptin increased significantly to levels higher or comparable to that seen in the Sham group. The mRNA expression of leptin was higher in the Labisia pumila-treated animals than in all other groups. In contrast, the elevated plasma resistin concentrations in OVX rats were significantly reduced in rats given ERT and Labisia pumila extracts. There was no difference in adiponectin levels in all groups. The uterus to body weight ratio of untreated OVX rats was significantly low compared to Sham, but showed dose-dependent increase upon treatment with Labisia pumila. The present study provides first evidence that Labisia pumila exerts uterotrophic effect and regulates body weight gain by modulating secretion of leptin and resistin, and expression of the adipokines in adipose tissues.

Protective Effect of Labisia pumila on Stress-Induced Behavioral, Biochemical, and Immunological Alterations.
Planta Med. 2010 Mar 9. Kour K, Sharma N, Chandan BK, Koul S, Sangwan PL, Bani S. Department of Pharmacology, Indian Institute of Integrative Medicine, Jammu Tawi, India.
The aim of the present study was to investigate the antistress potential of LABISIA PUMILA aqueous extract (LPPM/A003) using a battery of tests widely employed in different stressful situations. Pretreatment of experimental animals with LPPM/A003 caused an increase in the swimming endurance and hypoxia time and also showed the recovery of physical stress-induced depletion of neuromuscular coordination and scopolamine induced memory deficit. LPPM/A003 at graded doses reversed the chronic restraint stress (RST), induced depletion of CD4 (+) and CD8 (+) T lymphocytes, NK cell population, and corresponding cytokines expression besides downregulating the stress-induced increase in plasma corticosterone, a major stress hormone. In addition, LPPM/A003 reversed the chronic stress-induced increase in adrenal gland weight, serum alanine aminotransferase (ALT), alkaline phosphatase (ALP), and hepatic lipid peroxidation (LP) levels and augmented the RST induced decrease in hepatic glutathione (GSH), thymus and spleen weight. Thus, we conclude that LPPM/A003 has the ability to reverse the alterations produced by various stressful stimuli and therefore restores homeostasis.